A Simple Blood Test Predicts a Person’s Heart Disease Risk 30 Years Out, Study Finds | Amznusa.com

An anonymous Slashdot reader shared this report from NBC News:

A new approach to a routine blood test could predict a person’s 30-year risk of heart disease, research published Saturday in the New England Journal of Medicine found.

Doctors have long assessed their patients’ risk for cardiovascular disease by using a blood test to look at cholesterol levels, focusing particularly on LDL or “bad” cholesterol. But limiting blood testing to just cholesterol misses important โ€” and usually silent โ€” risk factors, experts say… Lead study author Dr. Paul Ridker, director of the Center for Cardiovascular Disease Prevention at Brigham and Women’s Hospital in Boston and his team found that in addition to LDL cholesterol, two other markers โ€” a type of fat in the blood called lipoprotein (a), or Lp(a), and an indicator of inflammation โ€” are important predictors of a person’s risk of heart attack, stroke and coronary heart disease…

In the study, the researchers analyzed data from nearly 30,000 U.S. women who were part of the Women’s Health Study. On average, the women were 55 years old when they enrolled in the years 1992 through 1995. About 13% โ€” roughly 3,600 participants โ€” had either a heart attack or stroke, had surgery to fix a narrowed or blocked artery, or died from heart disease over the 30-year follow-up period… All of the women had blood tests done at the beginning of the study to measure their LDL cholesterol, Lp(a) and C-reactive protein levels, a marker of inflammation in the body. These measurements, individually as well as together, appeared to predict a woman’s heart health over the next three decades, the study found.
Women with the highest levels of LDL cholesterol had a 36% higher risk for heart disease compared with those with the lowest levels. The highest levels of Lp(a) indicated a 33% elevated risk, and those with the highest levels of CRP were 70% more at risk for heart disease. When the three were looked at together, women who had the highest levels were 1.5 times more likely to have a stroke and over three times more likely to develop coronary heart disease over the next 30 years compared with women with the lowest levels.
All of the markers have been individually linked to higher risk of heart disease, but “all three represent different biological processes. They tell us why someone is actually at risk,” Ridker said.

Read more of this story at Slashdot.

ย An anonymous Slashdot reader shared this report from NBC News:

A new approach to a routine blood test could predict a person’s 30-year risk of heart disease, research published Saturday in the New England Journal of Medicine found.

Doctors have long assessed their patients’ risk for cardiovascular disease by using a blood test to look at cholesterol levels, focusing particularly on LDL or “bad” cholesterol. But limiting blood testing to just cholesterol misses important โ€” and usually silent โ€” risk factors, experts say… Lead study author Dr. Paul Ridker, director of the Center for Cardiovascular Disease Prevention at Brigham and Women’s Hospital in Boston and his team found that in addition to LDL cholesterol, two other markers โ€” a type of fat in the blood called lipoprotein (a), or Lp(a), and an indicator of inflammation โ€” are important predictors of a person’s risk of heart attack, stroke and coronary heart disease…

In the study, the researchers analyzed data from nearly 30,000 U.S. women who were part of the Women’s Health Study. On average, the women were 55 years old when they enrolled in the years 1992 through 1995. About 13% โ€” roughly 3,600 participants โ€” had either a heart attack or stroke, had surgery to fix a narrowed or blocked artery, or died from heart disease over the 30-year follow-up period… All of the women had blood tests done at the beginning of the study to measure their LDL cholesterol, Lp(a) and C-reactive protein levels, a marker of inflammation in the body. These measurements, individually as well as together, appeared to predict a woman’s heart health over the next three decades, the study found.
Women with the highest levels of LDL cholesterol had a 36% higher risk for heart disease compared with those with the lowest levels. The highest levels of Lp(a) indicated a 33% elevated risk, and those with the highest levels of CRP were 70% more at risk for heart disease. When the three were looked at together, women who had the highest levels were 1.5 times more likely to have a stroke and over three times more likely to develop coronary heart disease over the next 30 years compared with women with the lowest levels.
All of the markers have been individually linked to higher risk of heart disease, but “all three represent different biological processes. They tell us why someone is actually at risk,” Ridker said.

Read more of this story at Slashdot.ย 

The Amazon Marketplace: Empowering Sellers and Shaping Consumer Behavior

The Amazon Marketplace has emerged as a powerful force in the global economy, redefining how businesses operate and how consumers shop. Since its launch in 2000, Amazon Marketplace has grown into one of the largest online marketplaces in the world, with millions of sellers and an even larger base of customers. This platform has not only democratized e-commerce, providing opportunities for businesses of all sizes, but it has also significantly influenced consumer behavior. This article explores how the Amazon Marketplace empowers sellers and shapes consumer behavior.

Empowering Sellers: Opportunities and Challenges

The Amazon Marketplace has opened up unprecedented opportunities for sellers, from individual entrepreneurs to large corporations. One of the most significant benefits for sellers is the access to Amazon’s vast customer base. With over 300 million active users globally, Amazon provides a ready-made audience for sellers, eliminating the need for extensive marketing efforts to drive traffic to their products.

Lower Barriers to Entry

One of the most profound ways Amazon empowers sellers is by lowering the barriers to entry into the e-commerce space. Traditionally, setting up an online store required significant investment in website development, payment processing systems, and logistics. Amazon Marketplace simplifies this process by providing a platform where sellers can list their products, handle transactions, and even manage shipping through Amazonโ€™s Fulfillment by Amazon (FBA) service.

FBA, in particular, has been a game-changer for many small and medium-sized businesses. It allows sellers to store their products in Amazonโ€™s warehouses, where Amazon takes care of packing, shipping, and even customer service. This service not only reduces the logistical burden on sellers but also ensures that their products are eligible for Amazon Prime, which can significantly boost sales.

Global Reach

The global reach of Amazon Marketplace is another significant advantage for sellers. With Amazonโ€™s presence in numerous countries, sellers can tap into international markets with relative ease. Amazonโ€™s Global Selling program enables sellers to list their products in multiple countries, allowing them to expand their customer base far beyond their home market. This global reach is particularly beneficial for small businesses that may not have the resources to enter international markets independently.

Data and Analytics

Amazon provides sellers with valuable data and analytics tools that can help them optimize their listings and marketing strategies. Through the Seller Central dashboard, sellers have access to detailed reports on sales, customer behavior, and advertising performance. This data-driven approach allows sellers to make informed decisions about pricing, inventory management, and advertising, ultimately leading to better business outcomes.

Challenges for Sellers

However, selling on Amazon is not without its challenges. The competition on the platform is fierce, with millions of sellers vying for the attention of customers. To stand out, sellers must invest in optimizing their product listings, managing reviews, and running targeted advertising campaigns. Additionally, Amazonโ€™s fee structure, which includes referral fees, FBA fees, and other charges, can eat into sellersโ€™ profit margins, especially for those selling low-margin products.

Moreover, Amazonโ€™s control over the marketplace means that sellers are subject to its policies and regulations. This can be a double-edged sword; while Amazonโ€™s strict guidelines help maintain a level of quality and trust on the platform, they can also be restrictive for sellers. Policy changes, such as adjustments to fee structures or new regulations regarding product listings, can have a significant impact on sellersโ€™ businesses.

Shaping Consumer Behavior: Convenience and Choice

The Amazon Marketplace has not only empowered sellers but also transformed consumer behavior in profound ways. The platform has become synonymous with convenience, choice, and competitive pricing, which are key drivers of consumer decisions.

Convenience and Speed

One of the most significant impacts of Amazon on consumer behavior is the expectation of convenience and speed. Amazonโ€™s streamlined shopping experience, coupled with services like Amazon Prime, has set a new standard for online shopping. Consumers now expect fast, often same-day, delivery, easy returns, and a seamless shopping experience across devices. This has raised the bar for other e-commerce platforms and even brick-and-mortar stores, which have had to adapt to meet these heightened expectations.

The convenience offered by Amazon extends beyond just delivery speed. Features like one-click purchasing, personalized recommendations, and a user-friendly mobile app have made shopping on Amazon almost effortless. This ease of use has contributed to the platform becoming the go-to destination for many consumers, particularly for everyday purchases.

Broad Product Selection

Amazonโ€™s vast selection of products is another factor that has shaped consumer behavior. The marketplace offers a seemingly endless array of products across virtually every category, from electronics to groceries. This extensive selection is possible because of the millions of third-party sellers who list their products on the platform, alongside Amazonโ€™s own offerings.

This breadth of choice has shifted consumer expectations, leading to a preference for platforms that offer a wide variety of options. Consumers are now less willing to visit multiple websites or stores to find what they need, preferring the convenience of one-stop shopping. This trend has also put pressure on traditional retailers to expand their product offerings and improve their online shopping experiences.

Price Sensitivity and Competitive Pricing

Amazonโ€™s pricing strategies have also influenced consumer behavior, making customers more price-sensitive. The platformโ€™s dynamic pricing model, where prices can change frequently based on factors like demand and competition, encourages consumers to compare prices and seek out the best deals. Additionally, features like Amazonโ€™s price tracking tools and the ability to view historical prices have made consumers more aware of price fluctuations and more likely to wait for discounts before making a purchase.

This increased price sensitivity has impacted the broader retail landscape, forcing competitors to adopt more aggressive pricing strategies to stay competitive. It has also led to the rise of price comparison tools and apps, further empowering consumers to find the best deals.

The Role of Reviews and Ratings

Amazonโ€™s review system is another key factor influencing consumer behavior. Customer reviews and ratings have become a critical component of the decision-making process for many shoppers. Positive reviews can significantly boost a productโ€™s visibility and sales, while negative reviews can deter potential buyers. This has led to a culture where consumers rely heavily on the experiences of others to guide their purchasing decisions.

The importance of reviews has also created a new challenge for sellers, who must actively manage their reputation on the platform. This has given rise to practices like review solicitation and even, unfortunately, fake reviews. However, Amazon has taken steps to combat these practices, implementing stricter policies and algorithms to detect and remove fraudulent reviews.

Conclusion

The Amazon Marketplace has had a profound impact on both sellers and consumers, reshaping the e-commerce landscape in the process. By empowering sellers with access to a global customer base, powerful data tools, and logistical support, Amazon has lowered the barriers to entry for businesses of all sizes. At the same time, the platform has transformed consumer behavior, setting new standards for convenience, choice, and pricing.

As Amazon continues to evolve, its influence on the global economy and consumer culture will likely only grow. For sellers, the challenge will be to navigate the complexities of the platform and find ways to stand out in an increasingly crowded marketplace. For consumers, the Amazon Marketplace will continue to be a driving force behind the expectations and behaviors that define the future of shopping.